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Comparison between cerebroplacental ratio and umbilicocerebral ratio in predicting adverse perinatal outcome in pregnancies complicated by late fetal growth restriction: A multicenter, retrospective study

Fetal Diagnosis and Therapy Jun 18, 2021

Di Mascio D, Herraiz I, Villalain C, et al. - Researchers conducted a multicenter, retrospective cohort study of singleton pregnancies complicated by late fetal growth restriction (FGR) with the aim to clarify the role of cerebroplacental ratio (CPR) or umbilicocerebral ratio (UCR) in predicting adverse intrapartum and perinatal outcomes in these pregnancies. Pregnancies with a composite adverse outcome had lower median CPR absolute values (1.11 vs 1.22) and centiles (3 vs 4) when compared with those without it. There were higher median UCR absolute values (0.89 vs 0.82) and centiles (97 vs 96). However, a poor predictive value was indicated by the area under the curve, 95% confidence interval for predicting the composite adverse outcome. Overall findings suggest a low predictive value of CPR and UCR determined in the week prior to delivery to assess adverse intrapartum and perinatal outcomes in pregnancies with late FGR.

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