Comparison between 308-nm excimer light alone vs 308-nm excimer light and platelet-rich plasma in the treatment for localized vitiligo
Journal of Cosmetic Dermatology Nov 04, 2021
Elsaadany AE, El-Khalawany M, Elshahid AR, et al. - Findings demonstrate that no additional statistically significant benefit was conferred by the addition of platelet-rich plasma (PRP) to monochromatic excimer light (MEL) therapy, compared with MEL alone, in the treatment for localized stable vitiligo.
A total of 36 patients with at least 2 more or less symmetrical patches of localized stable vitiligo (72 patches) were included.
Each of the 2 vitiligo patches, for each patient, was randomized to receive either MEL therapy (twice weekly) with bi-weekly intradermal PRP (group A) or MEL therapy alone (group B) for a maximum of 4 months or till complete repigmentation.
In terms of the degree of repigmentation, patients’ level of satisfaction, and the frequency of side effects, there was no statistically significant difference between the 2 groups.
Recurrence occurred in only 3 patients, as noted at the end of the follow-up.
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