Stenberg E, et al. - Researchers compared different methods for mesenteric defects handling in laparoscopic gastric bypass surgery. They included 34,707 patients who had primary laparoscopic gastric bypass procedure from 2010 until 2015 reported to the Scandinavian Obesity Surgery Registry (SOReg), where the mesenteric defects closure method was identifiable. One hundred seventy-four (2.9%) patients with sutures, 592 (3.1%) with clips, and 278 (3.1%) in the non-closure group reported serious postoperative complication. Within 5 years after surgery, they noted lower reoperation rate for small bowel obstruction with sutures (cumulative incidence 6.9%) and clips (cumulative incidence 7.3%), compared to non-closure (cumulative incidence 11.2%). These findings support the safety and efficacy of using either non-absorbable metal clips or non-absorbable running sutures for closure of the mesenteric defects to reduce the risk for small bowel obstruction after laparoscopic gastric bypass surgery. For mesenteric defects closure, sutures seem slightly more effective and should remain gold standard.