Visser MM, Charleer S, Fieuws S, et al. - Since people with type 1 diabetes can continuously monitor their glucose levels on demand (intermittently scanned continuous glucose monitoring [isCGM]), or in real-time (real-time continuous glucose monitoring [rtCGM]), but it is uncertain whether switching from isCGM to rtCGM with alert functionality offers additional benefits, researchers performed this prospective, double-arm, parallel-group, multicentre, randomized controlled trial to compare rtCGM and isCGM in adults with type 1 diabetes (ALERTT1). This trial was carried out in six hospitals in Belgium. Adults with type 1 diabetes who had previously used isCGM were randomized (1:1) to receive either rtCGM (intervention) or isCGM (control). Between January 29 and July 30, 2019, 269 candidates were registered, of whom 254 were randomly assigned to rtCGM (n = 127) or isCGM (n = 127); 124 and 122 candidates finished the study, respectively. Switching from isCGM to rtCGM significantly improved time in range after 6 months of treatment in an unselected adult type 1 diabetes population, suggesting that physicians should consider rtCGM instead of isCGM to improve the health and quality of life of people with type 1 diabetes.