Whatmough S, et al. - In this retrospective study, researchers assessed the incidence and outcomes of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) among patients over a period of 23 years at a single tertiary center. Two cohorts of patients (1988–1999 and 2000–2010) were analyzed using Stata software (StataCorp, College Station, TX, US). They noted an increase in the number of patients diagnosed with AAV, from 2.2/million in 1988 to 10.3/million in 2010. In the earlier cohort vs in the later cohort, creatinine >500 μmol/L was seen in a higher proportion of patients (56.4% vs 30.2%). According to findings, AAV is now being diagnosed at an earlier stage, which results in improved outcomes. This improvement was possibly attributable to advances in AAV and chronic kidney disease management.