Shapiro DD, Wells SA, Best SL, et al. - Comprehensive clinical and pathologic data were obtained for individuals with non-metastatic renal cell carcinoma (RCC) with cT1b tumors after microwave ablation (MW), partial nephrectomy (PN) or radical nephrectomy (RN) from 2000-2018 in order to contrast perioperative and oncologic outcomes for individuals with clinical T1b RCC subsequent to treatment with MW, PN, or RN. A total of 325 individuals (40 MW, 74 PN, and 211 RN) were recognized. Patients treated with MW vs surgical individuals were elderly with greater Charlson comorbidity indices. In contrast with surgical individuals, the median length of hospitalization was shorter for MW. Two individuals relapsed following MW and had undergone repeat ablation without the following recurrence. Among MW, PN or RN, no variation in 5-yr metastasis-free survival or cancer-specific survival was discovered. Four MW individuals had a high-grade complication. Only former abdominal surgery prognosticated high-grade complications. Hence, in select comorbid individuals with clinical T1b RCC, microwave ablation was found out to be a feasible option for surgery.