Santos A, Mentula P, Pinta T, et al. - In this open-label randomized clinical trial involving 85 patients (26 male [31%]; mean [SD] age, 53.62 years [11.90]; 59 female [69%]; mean [SD] age, 57.08 [7.68]), experts explored whether sigmoid resection is better than conservative treatment in improving quality of life of patients with recurrent, complicated, or persistent painful diverticulitis. The findings suggested that laparoscopic sigmoidectomy was effective and improved quality of life within 6 months for patients with either recurrent, complicated diverticulitis or persistent pain after diverticulitis, but had a 10% risk of significant complications. Further results of the LASER trial will be reported if it is possible to analyze longer follow-up data.