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Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial

The American Journal of Emergency Medicine May 30, 2019

Mozafari J, et al. - The analgesic effect of intravenous fentanyl was compared with that of intranasal ketamine in renal colic patients. Among a total of 130 patients, 65 were administered one mg/kg of intranasal ketamine, and 65 were administered one μg/kg of intravenous fentanyl. Compared to fentanyl, ketamine was less effective in controlling renal colic-induced pain, and was correlated with a higher prevalence of side-effects; nevertheless, in conjunction with other medications, this pain can be effectively controlled with ketamine.
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