Comparative study between intrathecal dexmedetomidine and intrathecal magnesium sulfate for the prevention of post-spinal anaesthesia shivering in uroscopic surgery; (RCT)
BMC Anesthesiology Nov 03, 2019
Omar H, Aboella WA, Hassan MM, et al. - In this prospective randomized, double-blinded controlled investigation of 105 patients scheduled for uroscopic surgery at the Kasr El-Aini Hospital, researchers compared intrathecal dexmedetomidine vs intrathecal magnesium sulfate as a prophylactic against the occurrence of post-spinal anaesthesia shivering. Using randomization, patients were assigned to receive either 2.5 ml of hyperbaric bupivacaine 0.5% (12.5 mg) + 0.5 ml of normal saline (Group C; n = 35), or 2.5 ml of hyperbaric bupivacaine 0.5% (12.5 mg) + 25 mg of magnesium sulfate in 0.5 ml saline (Group M; n = 35), or 2.5 ml of hyperbaric bupivacaine 0.5% (12.5 mg) + 5 μg of dexmedetomidine in 0.5 ml saline (Group D; n = 35). Findings revealed the efficacy of intrathecal injections of both dexmedetomidine and magnesium sulfate in decreasing the incidence of post-spinal anaesthesia shivering. Thus, the use of magnesium sulfate was supported owing to its more physiological availability, more easy accessibility in most operating theatres and much less cost than dexmedetomidine.
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