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Comparative efficacy and tolerability of solifenacin 5 mg/day vs other oral antimuscarinic agents in overactive bladder: A systematic literature review and network meta-analysis

Neurourology and Urodynamics Evidence based | Nov 19, 2017

Nazir J, et al. - A comparative assessment was carried out of the efficacy and tolerability of solifenacin 5 mg/day with other oral antimuscarinic agents for the treatment of overactive bladder (OAB). It was noted that across the spectrum of OAB symptoms analyzed, the efficacy of solifenacin 5 mg/day was similar to other common antimuscarinics. It was disclosed to be more effective than tolterodine 4 mg/day in reducing incontinence and UUI episodes. Solifenacin 5 mg/day exhibited a lower risk of dry mouth compared with several agents.
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