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Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta‐analysis

Pediatric Allergy and Immunology Jul 09, 2020

Tan‐Lim CSC, Esteban‐Ipac NAR, Mantaring JBV, et al. - Researchers compared different types of probiotic strains with regard to effectiveness in treating pediatric atopic dermatitis. They identified all randomized controlled trials available from inception until January 31, 2020. Overall 22 studies with 28 different probiotic strains were analyzed. As far as efficacy was concerned, the top three ranked probiotic strains were Mix1 (Bifidobacterium animalis subsp lactis CECT 8145, Bifidobacterium longum CECT 7347, and Lactobacillus casei CECT 9104); Lactobacillus casei DN‐114001; and Mix6 (Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus casei, and Lactobacillus salivarius ). The highest ranked strain, in terms of safety, was Lactobacillus fermentum VRI‐003, while the lowest ranked strain was Lactobacillus rhamnosus GG. Overall, findings revealed that certain probiotic preparations are beneficial in decreasing allergic symptoms in pediatric atopic dermatitis.

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