Malhotra A, et al. - In this investigation, researchers assessed the effectiveness of endovascular thrombectomy (EVT) in acute stroke due to large occlusion of vessels for elderly patients >80 years of age. From a societal perspective, a Markov decision analytic model was constructed to evaluate health outcomes in terms of quality-adjusted life years (QALYs) after EVT for acute ischemic stroke due to large vessel occlusion in patients over the age of 80. From the most recent/comprehensive literature, age-specific input parameters were obtained. The data presented in this work showed the impact of relevant factors in patients over 80 years of age on the effectiveness of EVT. Morbidity and mortality have a significant impact on outcomes in both healthy and disabled patients at baseline, following both IVT and EVT strategies. Better identification of non-IVT patients would optimize the selective use of EVT thereby enhancing its efficacy.