Kwak Y, et al. – The scientists explored the gene copy number (GCN) variation of EGFR, HER2, c–MYC, and MET in patients with primary colorectal cancer (CRC). They examined GCN variation of four genes in a large sample of Korean CRC patients. They concluded that the amplification status was not associated with patient outcome. However, the GCN gain and GCN status according to the ASCO/CAP 2013 guideline were independent prognostic factors, they added.