Sayar SK, et al. - This study was undertaken to explore the demographic and clinical features of bullous pemphigoid (BP) patients in a large series from Turkey, ascertain the prevalence of pre-existing neurological and systemic disorders, and evaluate the relationship between the existence of certain comorbidities and basal serum titers of anti-BP180 and 230 immunoglobulin G autoantibodies. Researchers retrospectively examined data from 145 patients who were consecutively diagnosed with BP at our center between 1987 and 2017 and compared with 310 age- and gender-matched control individuals. The results showed that neurological disorders, especially stroke, and malignancies were found to be significantly connected to the occurrence of BP in the selected Turkish population among the pre-existing comorbidities. The outcomes suggested that the high titers of serum anti-BP180 and 230 antibodies at the time of BP diagnoses may highlight undiagnosed pre-existing neurological disorders by provoking clinical suspicion.