Neupane SP, et al. – The purposes of this study were to investigate how alcohol use disorder (AUD) patients with post–traumatic stress disorder (PTSD) differed from those without PTSD in terms of demography, drinking patterns and C–reactive protein, inflammatory cytokines, tryptophan metabolism parameters, and brain–derived neurotrophic factor (BDNF). The results obtained from the study support routine trauma screening in AUD treatment samples and screening for risky drinking in trauma populations to help guide interventions. The expected aberrations in neuroimmune functioning might not be noticed when investigated in a sample with multiple psychiatric morbidities.