den Harder AM, et al. - Researchers performed a cross-sectional study within the Utrecht Patient Oriented Database (UPOD) to examine the links between commonly available hematological biomarkers and the coronary artery calcification (CAC) score, which may shed light on the pathophysiology of coronary calcifications and subclinical coronary artery disease. Study participants were patients with suspected or known coronary artery disease who underwent CT CAC scoring, as well as standard hematology analysis within 3 months of CT. The associations were assessed using linear regression adjusted for potential confounders. Findings corroborated the known association of red blood cell distribution width with the CAC score. The identified new markers related to a higher CAC score were the fraction of immature reticulocytes, coefficient of variation of neutrophil lobularity, and mean lymphocyte cell size.