Common variants in IL-1RN, IL-1β and TNF-α and the risk of ovarian cancer: A case control study
Central European Journal of Immunology Aug 26, 2017
Ben Ahmed A, et al. – The relationship between polymorphisms in IL–1β (–511C>T), IL–1RN VNTR, TNF–α (–308G>A), and TNF RII (–322 VNTR) and ovarian cancer (OC) risk in Tunisian women, was investigated. This study suggested a significant association between IL–1RN VNTR, IL1–β (–511), TNF–α (–308) and OC susceptibility in Tunisian women. This finding confirmed a role for altered inflammatory response in ovarian cancer pathogenesis.
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