Combining topical tretinoin with mometasone furoate in the treatment of vulvar lichen sclerosus: Results of dermoscopic assessment
Dermatologic Therapy Oct 22, 2018
Corazza M, et al. - Researchers sought to compare dermoscopic changes on vulvar lichen sclerosus (VLS) induced by two different 12-week treatment protocols, namely mometasone furoate 0.1% ointment plus tretinoin 0.05% cream in short-contact therapy (group A) vs the same corticosteroid plus emollient (group B). Both in terms of mean score change and in the number of patients showing changes, they did not notice any significant difference in the two protocols for any of the dermoscopic parameters at the control visit. Nonetheless, a therapeutic benefit may be suggested by the complementary action of the two molecules, significant changes in the dermoscopic features of VLS were not induced by the association of tretinoin in short contact therapy with a potent corticosteroid compared with the same corticosteroid alone.
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