Huang Y, et al. - In this study, researchers created a cumulative score for assessment new-onset hypertension risk, consisting of seven risk factors: age, resting heart rate, overweight or obesity, dyslipidemia, hyperuricemia, impaired glucose regulation, and impaired estimated glomerular filtration rate (eGFR). Overall 23,665 participants free from hypertension at baseline were included. A composite, individual-level cumulative score was calculated (no=0 point; yes=1 point; total range 0–7 points) and its link with the risk of hypertension was assessed using Cox regression. For those with 2, 3, and at least 4 points, compared with those with 0 points, the adjusted hazard ratios for the development of hypertension were 1.61, 2.05, and 2.77, respectively. A significant risk of new-onset hypertension was observed in correlation with age, resting heart rate, overweight or obesity, dyslipidemia, hyperuricemia, impaired glucose regulation, and impaired eGFR. An accumulation of risk was evident when these risk factors were combined.