Colledanchise KN, et al. - In this cross-sectional study, 500 individuals underwent carotid and femoral ultrasound after coronary angiography in order to ascertain gender-specific plaque quantification markers by vascular ultrasound for recognizing important, obstructive coronary artery disease (CAD). Important CAD was seen in 231 men and 78 women. The most exact recognizer of CAD in men was a combined evaluation of femoral bifurcation and carotid maximal plaque height, however, it was a poorer indicator of CAD in women. On the contrary, via a combined analysis of common femoral and carotid total plaque area, the most robust recognition of CAD in women was attained. At this value, more than half of females who had false-positive stress test results, accurately recognized as having no notable CAD. Hence, in both genders, combined femoral and carotid plaque burden evaluations efficiently found out important disease. Moreover, in women, in whom traditional screening tools are less efficient, vascular ultrasound could have certain value for cardiovascular risk stratification.