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Combinatory activity of linezolid and levofloxacin with antituberculosis drugs in Mycobacterium tuberculosis

Tuberculosis May 22, 2018

de Souza Santos NC, et al. - Researchers ascertained the in vitro activity of isoniazid (INH)/rifampicin (RIF)/levofloxacin (LVX) and INH/RIF/linezolid (LNZ) combinations in resistant M. tuberculosis. In M. tuberculosis H37Rv, susceptible and 10 resistant clinical isolates by three-dimensional checkerboard, the combinations activities were evaluated. As per data, in the treatment of resistant TB, attention for the potential use of INH/RIF/LVX and INH/RIF/LNZ combinations was suggested.
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