Xuan Q, et al. - In this retrospective analysis, researchers assessed pretreatment albumin to globulin ratio (AGR) combined with neutrophil to lymphocyte ratio (NLR) for clinical significance in cases with triple negative breast cancer (TNBC). Overall 286 cases were examined. At optimal cut-off points of 1.63 for an AGR and 2.93 for NLR, discrimination of patients with good vs poor prognosis was enabled. An increased area under the receiver operating characteristic curves was generated with combined with AGR and NLR (CO-AN) vs AGR and NLR individually. Poor survival was reported in association with low AGR/high NLR in Kaplan–Meier analysis. A significant as well as independent association of high AGR levels, low NLR levels, and CO-AN<1 with favorable disease-free survival was revealed in univariate and multivariate analyses. In patients with TNBC, the utility of AGR and NLR levels as prognostic biomarkers for disease-free survival was suggested. Also, a possible greater predictive value of CO-AN vs AGR and NLR was indicated in these patients.