Kihira S, Koo C, Mahmoudi K, et al. - This study was carried out to assess if MR imaging features will add diagnostic value when combined with clinical biomarkers to predict positive findings of spondylodiscitis on pathology and/or microbiology from the percutaneous biopsy. Researchers conducted a retrospective single-center institutional review board–approved study to evaluate patients with radiologically suspected spondylodiscitis and having undergone percutaneous biopsies. They obtained demographic characteristics, laboratory values, and tissue and blood cultures. They applied pathology and microbiology results as endpoints. They conducted multivariate logistic regression and receiver operating characteristic analysis to ascertain an optimal combination of imaging and clinical biomarkers in predicting positive findings on pathology and/or microbiology from percutaneous biopsy suggestive of spondylodiscitis. A total of 72 patients were included in the study, of whom 33.3% (24/72) had spondylodiscitis. The data indicate that epidural enhancement on MR imaging added diagnostic value when combined with clinical biomarkers to help prognosticate which patients undergoing percutaneous biopsy will have positive findings for spondylodiscitis on pathology and/or microbiology.