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Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

BMC Pulmonary Medicine Apr 08, 2019

Bhuiyan MU, et al. - In a sample of Western Australian children (≤17 years) hospitalized with radiologically-confirmed community-acquired pneumonia, researchers investigated the ability of clinical features and blood inflammatory biomarkers for differentiating bacterial from viral pneumonia, as this step is important for guiding targeted management and judicious use of antibiotics. They compared clinical features and biomarker levels between cases with definite bacterial pneumonia, presumed viral pneumonia, and other pneumonia cases. Compared with C-reactive protein (CRP) alone, combining elevated CRP with the presence or absence of clinical signs/ symptoms enabled better differentiation of definite bacterial from presumed viral pneumonia.
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