Colorectal cancer in inflammatory bowel diseases: A population-based study (1976–2008)
Inflammatory Bowel Disease Oct 18, 2019
Peyrin-Biroulet L, et al. - In this population-based cohorts, researchers analyzed the incidence, features, treatment, and prognosis of inflammatory bowel disease (IBD)-associated colorectal cancer (CRC). All cases of IBD-associated CRC have been identified among the 19,451 new cases of CRC recorded in the Burgundy digestive cancer registry between 1976 and 2008. Using univariate and multivariate relative survival, prognosis was determined. They identified 38 IBD-associated CRC. Data reported that the overall world age-standardized incidence of IBD-associated CRC per 100,000 was 0.11 for men and 0.06 for women. Only age was independently linked to IBD-associated CRC. Besides age, IBD-associated CRC's characteristics were similar to those of non-IBD CRC. CRC prognosis may be poorer in IBD patients than in non-IBD patients.
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