Yu SY, et al. - Because endoscopic resection is one of the primary colorectal cancer prevention procedures, researchers wanted to know how endoscopic therapy affects the gut microbiota. Participants in the study were 20 patients who had endoscopic resection of colorectal adenoma and analyzed the fecal microbiota before and 3 months after adenoma resection. Despite few changes in the overall microbial structure following adenoma resection, the abundance of Parabacteroides showed a significant postoperative increase and the microbiota signature of Parabacteroides, Streptococcus and Ruminococcus exhibited an optimal discriminating postoperative status performance with the area under curve 0.788. According to this prospective study, fecal microbial changes indicate the moderate effect of adenoma resection on gut microbiota and lay the groundwork for adenoma recurrence microbial prediction.