Velickaite V, et al. - The association of cognitive performance with the degree of brain atrophy, cerebrospinal fluid (CSF) biomarker levels and neuropathology was investigated in a cohort of aged men. Findings demonstrated that cognitive performance was weakly correlated with medial temporal atrophy (MTA), whereas, there existed no correlation between the various neuroradiological, biochemical and neuropathological measures. Therefore, Alzheimer’s disease (AD) biomarkers appear to be less informative in subjects of an advanced age.