Everitt HA, Landau S, O'Reilly G, et al. - Researchers conducted this follow-up study to assess longer-term (24 months) clinical results of telephone cognitive behavioural therapy (CBT) and web CBT vs treatment as usual (TAU) in adults with refractory irritable bowel syndrome (IBS). Five hundred fifty-eight adults with refractory IBS were randomly allocated to receive either therapist-delivered telephone CBT (telephone-CBT group), web-based CBT with minimal therapist support (web-CBT group), or TAU group and were followed up for 12 months ni the ACTIB three-group, randomised, controlled trial. According to results, sustained improvements in IBS were observed in both CBT groups vs TAU at 24-month follow-up, although some previous gains were reduced vs the 12-month outcomes. IBS-specific CBT has the potential to achieve long-term improvements in IBS within the usual clinical setting. A long-term patient advantage could be achieved by increasing access to CBT for IBS. There have been no treatment-related adverse events.