Kumral E, Bayam FE, Özdemir HN., et al. - In this study, the clinical, neurocognitive, and behavioral characteristics of isolated precuneal cortex (PC) infarcts were explored. Neuropsychological and behavioral findings in 12 patients with isolated PC infarct among 3,800 patients with ischemic stroke were evaluated. Researchers firstly overlapped the ischemic area of patients with specific cognitive disorders and patients without specific cognitive disorders to ascertain the most frequently affected brain locus in patients. Using the “subtraction plot” function of MRIcroGL, both overlap maps were compared. The data revealed a wide variety of neuropsychological and behavioral disorders in patients with precuneal infarct. Damage within the anterior precuneal region might lead to consciousness disorders (25%), self-processing impairment (42%), visuospatial disorders (58%), and lesions in the posterior precuneal region caused episodic and semantic memory impairment (33%), as determined via Lesion topographical analysis. Further trials are required to achieve a proper definition of the function of the precuneus in relation to the extended cortical areas. The evidence suggested that PC region infarcts have been found to predict a source of embolism from the large arteries or heart.