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Coffee consumption is associated with lower liver stiffness: A nationally representative study

Clinical Gastroenterology and Hepatology Oct 10, 2021

Niezen S, Mehta M, Jiang ZG, et al. - This study among US adults revealed that coffee consumption is related to lower liver stiffness but not steatosis as measured by controlled attenuation parameter (CAP).

  • This is an analysis of 4,510 individuals >20 years old from the 2017-2018 NHANES study.

  • The links between liver stiffness measurements (LSM) > 9.5 kpa or CAP and coffee intake were examined.

  • A 0.9 lower kPa was seen in those who drank >3 cups of coffee but not other drinks.

  • Drinking >3 cups of coffee was protective for LSM > 9.5 kpa (OR: 0.4).

  • Coffee intake was associated with lower LSM even after adjusting for sugar-sweetened beverage consumption and Healthy Eating Index-2015.

  • The protective nature of coffee intake was not due to caffeine and persisted in participants irrespective of their diet quality.

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