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Coagulative function assessed preoperatively via the clot formation and lysis assay as a prognostic factor for blood loss in adolescents undergoing posterior spinal fusion for idiopathic scoliosis

Paediatric Anaesthesia Nov 08, 2019

Fernandez AM, et al. - Among adolescent idiopathic scoliosis patients undergoing posterior spine fusion, researchers prospectively searched putative prognostic factors for intraoperative blood loss and perioperative blood transfusion, with a focus on clinical features, surgical factors, and preoperative evaluation of overall coagulative and fibrinolytic functions in plasma using the clot formation and lysis (CloFAL) assay. Participants were 74 patients, with a median age of 14.8 years. Findings revealed an independent association of increased coagulative function, measured preoperatively using the CloFAL assay, with reduced intraoperative blood loss in adolescents undergoing posterior spinal fusion for idiopathic scoliosis.
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