Benediktsson S, et al. - Researchers determined whether prothrombin time (PT-INR) and activated partial thromboplastin time (APTT) at admission have any role in predicting outcome in the critically ill patient following adjustment for severity of illness measured with Simplified Acute Physiology Score 3 (SAPS 3). This study was performed on 3,585 ICU-patients. To report organ failure, the focus was laid on days alive and free (DAF) of vasopressors and invasive ventilation, the requirement of continuous renal replacement therapy and Acute Kidney Injury Network creatinine score. Findings revealed a link of APTT prolongation with mortality and all morbidity outcomes except the DAF ventilator. A link of PT-INR increase at admission with DAF vasopressor and DAF ventilator was also noted. Experts found a correlation of APTT and PT-INR at admission with morbidity, which was not accounted for in the SAPS 3 model.