Natsis NE, et al. - Given that coagulase-negative staphylococcus organisms are a normal flora of human skin, however these bacteria can also be pathogens in skin and soft tissue infections, experts evaluated the skin and soft tissue infections caused by coagulase-negative staphylococcus species. Particularly in older and/or immunocompromised individuals, skin and soft tissue infections could be resulted by albeit less common, coagulase-negative staphylococcus organisms. The growth of coagulase-negative staphylococcus organisms occurs most commonly in cultures of abscesses and paronychia. Hence, consideration of coagulase-negative staphylococcal organisms always as normal flora would be wrong, instead, they should be considered as causative pathogens. Data demonstrated their susceptibility to the antibiotics used to treat methicillin-sensitive Staphylococcus aureus.