Bai J, et al. - Given that small cell carcinomas (SmCCs) were considered the most aggressive type of neuroendocrine carcinomas, researchers analyzed the clinicopathological features and determined the factors related to the survival of this rare cancer. Using prospectively extracted data from the Surveillance, Epidemiology and End Results (SEER) database between 1988 and 2016, a population-based study was conducted to examine clinical features and prognosis of SmCC of the salivary gland. A total of 198 patients with SmCC of the salivary gland have been identified with an average age of 72.6 ± 12.4 and a male to female ratio of 3.4:1. Most patients' lesions were in the parotid gland. Data reported that the median overall survival was 25.0 months of all patients. According to findings, SmCC of the salivary gland is a rare disease, and old age, lymph node, distant metastases, and radiotherapy were significantly linked to prognosis. More cases with adequate information are needed in order to understand this disease more thoroughly.