Clinicopathological and molecular implications of aberrant TTF-1 expression in colorectal carcinomas: An immunohistochemical analysis of 1,319 cases using three different antibody clones
Histopathology Sep 20, 2017
Bae JM, et al. - During this study, the TTF-1 expression status was scrutinized in colorectal carcinomas (CRCs) cases using three different antibody clones. The data affirmed that the frequency and characteristics of aberrant TTF-1 expression in CRCs differed, based on the antibody clone. Aberrant TTF-1 expression identified via clone SPT24 or SP141 could be encountered preferentially in distally located, conventional pathway-type CRCs.
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