Yang Y, et al. - Researchers analyzed females (n=90) between the ages of 30 and 64 years (mean, 44 years) who had polyacrylamide hydrogel (PAAG)-injected breast augmentation, to summarize clinical and pathological features of these cases, including 2 cases of breast cancer developed post-PAAG injection. They found that PAAG-injected breast augmentation had various and complex long-term complications, including masses (75.58%), pain (45.35%), migration (22.09%), deformation (18.60%), infection (16.28%), induration (4.65%), and psychological fear (2.33%). Pathologically, they found a link of these complications with foreign body reaction, fibrosis, and inflammation. Atrophy, adenosis, ductal carcinoma in situ, and invasive carcinoma were shown by mammary gland around the gel in 18 cases (20.00%), 33 cases (36.67%), 1 case (1.11%), 1 case (1.11%), respectively.