Siddiqui SH, et al. - In this multi-institutional study, researchers, for the first time, analyzed clinicopathologic traits and prognostic factors associated with outcomes in pediatric sinonasal rhabdomyosarcoma (RMS), an aggressive and rare malignancy. This is the largest pediatric sinonasal RMS study, which assessed National Cancer Database data from 2004 to 2013 for all cases of malignant sinonasal RMS in the pediatric population, ultimately identifying a total of 157 cases. The most common primary sites were the nasal cavity and maxillary sinus. Alveolar, followed by embryonal type, was the most common histology. Five-year overall survival was 55.2%, and metastatic disease was correlated with a poorer 5-year OS rate. Improved survival was associated with the maxillary sinus site. Findings suggested that clinical risk groups of Intergroup Rhabdomyosarcoma Study Group may be useful in stratifying low-prognosis high-risk patients.