Gogia A, Deo SVS, Sharma D, et al. - For the first time, patients with metastatic breast cancer from India were examined comprehensively for long-term outcome. In this ambispective review of approximately 1,800 patients (Median age at presentation: 49 years) who were registered in breast cancer clinics, nearly 410 (22.8%) patients presented with up-front metastasis. Researchers obtained clinical, pathologic, and radiologic details from the medical records. For the cohort, they observed median progression-free survival of 14.2 months (95% CI, 12.7 to 16.8 months), and median overall survival (OS) of 31.7 months (95% CI, 25.8 to 38.2 months). They observed better outcomes in correlation with HR-positive status, oligometastasis, and good performance status, whereas inferior OS in correlation with triple-negative breast cancer and liver and brain metastasis.