Hoshiai S, Masumoto T, Hanaoka S, et al. - Researchers focused on the contribution of temporal subtraction (TS) computed tomography (CT) for the detection of vertebral bone metastases. Bony landmark detection, bone segmentation with a multiatlas-based method, and spatial registration were all included in TS CT calculation. They visualized temporal increase and decrease of the CT values in blue and red, respectively. Analysis of paired CT images of 20 patients with cancer and newly-developed vertebral metastases was performed. This study also included control CT assessments of 20 different patients. Findings were suggestive of the possible utility of TS CT in detecting vertebral metastases, as nearly all the vertebral metastases were shown to be favorable visualization. TS CT particularly aided radiology residents in the detection of vertebral arch metastases. Clear visualization of vertebral metastases was enabled with TS CT.