Ferreira J, et al. – Authors performed analysis of articles on the clinical usefulness of catheter–drawn blood samples and catheter tip cultures for the diagnosis of intravascular catheter–related bloodstream infection (CRBSI) in neonates. In this work, most of the studies analyzed cultures from the central venous catheter tip and catheter fragments for the diagnosis of CRBSI in neonatal populations. Results revealed that the analysis of the catheter–drawn blood samples and catheter tip cultures, paired with peripheral blood cultures, were efficient methods for the diagnosis of CRBSI in neonates.