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Clinical, trichoscopy, and light microscopic findings in hypohidrotic ectodermal dysplasia: Report of 21 patients and a review of the literature

Pediatric Dermatology Apr 22, 2021

Peña‐Romero AG, Sáez‐de‐Ocariz M, Toussaint‐Caire S, et al. - Since hair findings in hypohidrotic ectodermal dysplasia (HED) have been poorly characterized in larger series, researchers conducted this cross‐sectional study to characterize scalp and hair findings of patients with HED clinically and with trichoscopy and light microscopy. The sample consisted of 21 pediatric HED patients. Seventeen of the 21 patients (81%) were men. Hair findings in HED were similar to those reported in previous studies in this series. However, the authors report two new clinical and two trichoscopic findings: decreased hair density mainly in the temporal and occipital regions, oblique upwards occipital hair follicles orientation, angled hairs, and short curly pigtail hairs. Such heterogeneous results may reflect the multiple factors and signaling pathways that can be affected in these syndromes.

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