Cornelissen L, et al. - This study was designed to assess the associations between end-tidal sevoflurane (ETsevoflurane) concentration, age and frontal electroencephalographic (EEG) spectral properties in determining recovery of clinical–behavioural signs during emergence from sevoflurane in children 0 to 3 years of age, with and without exposure to nitrous oxide. Researchers hypothesized that clinical signs occur sequentially during emergence and that for infants aged more than 3 months, changes in alpha EEG power are correlated with clinical–behavioural signs. They observed the sequential occurrence of several clinical signs during emergence that was independent of exposure to nitrous oxide. They observed a poor correlation of eye position with other clinical signs or ETsevoflurane. In children more than 3 months, EEG spectral characteristics could help predicting clinical–behavioural signs.