Yamashita Y, Yamano Y, Muro Y, et al. - This study was intended to construct an enzyme-linked immunosorbent assay (ELISA) for measuring them to investigate the clinical features of patients with anti-NOR90 antibodies. Researchers included serum samples from 1,252 patients with various conditions from Nagoya University Hospital and 244 patients with idiopathic interstitial pneumonia (IIP) from Tosei General Hospital. They further evaluated anti-NOR90 antibodies by an ELISA using the recombinant protein produced by in vitro transcription/translation. ELISA is useful for their detection, although anti-NOR90 antibodies are rarely found in clinics. There is a need for further studies to confirm the association of anti-NOR90 antibodies with ILD and cancer in systemic sclerosis and IIP patients.