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Clinical significance of advanced lung cancer inflammation index, a nutritional and inflammation index, in gastric cancer patients after surgical resection: A propensity score matching analysis

Clinical Nutrition Jul 24, 2020

Yin C, Toiyama Y, Okugawa Y, et al. - This retrospective study was undertaken to clarify the predictive ability of the advanced lung cancer inflammation index (ALI) in gastric cancer (GC) for surgical as well as oncological results. To certify the results, propensity score matching analysis was performed. This study involved 620 GC patients undergoing gastrectomy. A significant link between preoperative low ALI with advanced tumor–node–metastasis stage classification was identified. Poorer overall survival (OS) and disease-free survival was observed in patients with low ALI vs those with high ALI; reduced ALI was identified as an independent prognostic factor for OS in multivariate analysis. Overall, among GC patients, those carrying a high risk of adverse perioperative and oncological outcomes could be identified via quantification of preoperative ALI.

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