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Clinical significance of acute and chronic ischaemic lesions in multiple cerebral vascular territories

European Radiology Feb 05, 2019

Erdur H, et al. - Via data from the 1,000+ study–a prospective, observational 3-Tesla MRI cohort study– researchers examined if there was a relationship between acute and chronic ischemic lesions in a multiple territory lesion pattern (MTLP) detected by 3-Tesla MRI and stroke etiology, explicitly atrial fibrillation-associated stroke. Findings suggested an association of advanced age, atrial fibrillation, aortic arch atherosclerosis, malignant disease, and lower estimated glomerular filtration rate (eGFR) with multiple territory lesion pattern defined by either acute or chronic lesions (MTLPa/c). However, only malignant disease and lower eGFR were related to multiple territory lesion pattern defined by acute lesions only (MTLPa). Bearing in mind not only acute, but also chronic ischemic lesions, identification of atrial fibrillation-associated or aorto-embolic stroke can be easier.

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