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Clinical, radiological, and laboratory characteristics and risk factors for severity and mortality of 289 hospitalized covid‐19 patients

Allergy Aug 28, 2020

Zhang JJ, Cao YY, Tan G, et al. - Researchers assessed 289 hospitalized laboratory‐confirmed COVID‐19 patients in order to determine the risk factors linked with the severity of COVID‐19 patients and the mortality of severe patients. Based on the severity and outcomes of the patients, they were stratified into three groups: nonsurvived (n = 49), survived severe (n = 78), and nonsevere (n = 162) groups. Observations revealed distinct clinical and laboratory characteristics of survived severe and nonsurvived COVID‐19 patients, which were separated by principle component analysis. Following were the identified risk factors for mortality of severe COVID‐19 patients: elder age, increased number of affected lobes, higher levels of serum C‐reactive protein, chest tightness/dyspnea, and smoking history. Disease progression and clinical outcome of severe patients could be identified via assessing longitudinal changes in laboratory findings.

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