Ali BA, Salman M, Ghanem KM, et al. - Clinical features and outcomes of 38 individuals treated between 2001 and 2012 at a single institution in Lebanon were retrospectively analyzed in order to investigate prognostic factors and treatment outcome in pediatric osteosarcoma at a multidisciplinary center in Lebanon, as these have not been sufficiently explained to date in developing countries. The long bones around the knee (n = 34) was the most prevalent primary site. Six had metastatic disease to lungs, and three, a synchronous multifocal bone disease along with lung metastases. Nonlower extremity sites, metastasis, poor degree of necrosis, and delay of more than 4 weeks in local control were adverse prognostic factors whereas, in the bivariable analysis for survival and disease recurrence, the only degree of necrosis was a prognostic predictor. Hence, in a multidisciplinary cancer center in Lebanon, the treatment of pediatric osteosarcoma led to comparable survival to those in developed countries. Moreover, delay in local control was related to worse outcomes. Poor degree of necrosis at the time of local control was the only statistically important inferior outcome predictor.