Martin DM, et al. - In medication-resistant patients, researchers investigated the feasibility, safety, and clinical efficacy of combining transcranial direct current stimulation (tDCS) with a psychological intervention which targets dysfunctional circuitry related to emotion regulation in depression, Cognitive Emotional Training (CET). tDCS combined with CET was observed to be associated with significant antidepressant efficacy and improved emotion recognition. Findings thus suggest that tDCS combined with CET could have potential for optimising the antidepressant efficacy of tDCS in medication-resistant patients.