Conway JL, Lukovic J, Ferguson SE, et al. - Individuals with unresectable stages II to IVA endometrial cancer (n = 59) who were treated with curative intent between January 2000 and March 2018 were recognized in order to ascertain the outcomes of individuals with unresectable endometrial cancer managed with definitive or neoadjuvant radiation (RT) and/or chemotherapy. Seventeen patients got neoadjuvant chemotherapy, 28 neoadjuvant radiation, and 14 definitive RT and 39 underwent surgery. Younger age, endometrioid histology, and earlier stage were factors related to greater odds of surgical resection. Younger age, endometrioid histology, and surgical resection were significantly connected to higher overall survival. Surgical resection was also related to higher DFS. Surgical resection after RT and/or chemotherapy for locally advanced, unresectable endometrial cancer was correlated with greater disease-free survival and overall survival and more inclined to be accomplished in endometrioid subtypes.