Birbal RS, et al. - In this retrospective, interventional case series, researchers estimated the utility and clinical consequences of Descemet membrane endothelial keratoplasty (DMEK) in eyes with a glaucoma drainage device (GDD). THey observed cumulative graft success rate of 89% at 1 year postoperatively in Kaplan-Meier survival analysis. They noticed an improvement in best-corrected visual acuity (BCVA) by ≥2 Snellen lines in 11 eyes and remained stable in 4 eyes, at 1 year postoperatively. They recorded postoperative complications up to 2 years postoperatively like pupillary block in 1 eye (reversed by partial air removal), visually significant graft detachment requiring rebubbling in 5 eyes, allograft rejection successfully reversed with topical steroids in 2 eyes, secondary graft failure in 2 eyes, and cataract in 1 of 3 phakic eyes. Although the presence of a GDD might decrease graft survival times and could pose risk for frequent regrafting, they suggested that DMEK provided acceptable clinical outcomes.